Infarmed’s recent approval of esketamine for the treatment of treatment-resistant depression marks an important step in addressing the needs of thousands of people in Portugal. This development offers a new treatment option for those who have tried multiple conventional antidepressants without success.
At The Clinic of Change, this innovative treatment is now available as part of a rigorous protocol and is supervised by specialized healthcare professionals.
What is Esketamine?
Esketamine is a fast-acting medication indicated for adults diagnosed with treatment-resistant depression—that is, patients who have not experienced significant clinical improvement after at least two appropriate courses of antidepressant treatment.
This intranasal medication is effective in rapidly reducing symptoms such as deep sadness, anxiety, loss of interest, extreme fatigue, changes in sleep and appetite, and even suicidal thoughts. Its rapid onset of action—within 1 to 4 weeks—makes it a valuable option in urgent situations.
How does treatment work at The Clinic of Change?
At our clinic, esketamine is administered exclusively under a doctor’s prescription and strict clinical supervision. Treatment takes place in a safe and controlled environment, with close monitoring by experienced mental health professionals.
The medication is administered via a nasal device during scheduled sessions. The frequency and dosage are adjusted on an individual basis, taking into account each patient’s medical history and needs.
Quando é indicada a Esketamina?
A esketamina pode ser recomendada nos seguintes casos:
- Diagnosis of treatment-resistant depression
- Urgent clinical situations involving severe depressive episodes
- Presence of suicidal ideation, requiring a rapid response
Before beginning treatment, each case is evaluated by the medical team at The Clinic of Change to ensure that esketamine is a clinically appropriate and safe option for the patient.
Specialized support
At The Clinic of Change, we support each patient throughout the entire process. Our mission is to ensure not only safety, but also the effectiveness and compassionate care of the treatment, while respecting each person’s needs and vulnerabilities.
Learn more about the Esketamine Program here and contact us.
The Clinic of Change is a healthcare provider registered under number E166508, located at Rua das Picoas, 12, Ground Floor, 1050-173 Lisbon, with operating license number 22863/2023, and registered with the ERS under number 39467.
